Hospital & Clinics
Endoscope Reprocessing - The Cleaning Process
Flexible endoscopes are essential diagnostic and therapeutic medical devices; however, they are also recognised as one of the most complex devices to reprocess.
Numerous published reports have demonstrated that healthcare associated infection outbreaks are more frequently linked to contaminated endoscopes than to any other type of reusable medical device.
During clinical use, endoscopes come into contact with blood, mucus, tissue debris, and other organic body fluids. Their long, narrow channels and complex internal structures provide ideal conditions for bacterial adhesion and microbial retention.

Effective cleaning is the most critical step in the endoscope reprocessing cycle. Proper cleaning is essential to remove organic and inorganic soil and to prevent the development of biofilms that can compromise subsequent disinfection or high-level disinfection processes.
The cleaning step consists of thorough mechanical cleaning of both the external surfaces and internal channels of the endoscope. This includes careful brushing of all accessible channels using an appropriate detergent solution, followed by thorough flushing and rinsing with suitable water quality.
For this reason, endoscopes should be cleaned immediately after use and prior to the disinfection step using a validated enzymatic detergent specifically designed for endoscope reprocessing. NOSOZYM and NOSOZYM 6 PLUS contain a combination of specific and highly stabilised enzymes. The enzymes break down the soil into tiny fragments, making them water soluble and thus easier to remove by rinsing.
NOSOZYM and NOSOZYM 6 PLUS are compatible with all major brands of endoscopes.
They have been tested and approved by PENTAX MEDICAL®.
Endoscope Reprocessing - Endoscope high level disinfection
Following thorough cleaning and initial rinsing, high-level disinfection (HLD) is recommended for flexible endoscopes and other semi-critical medical devices.
During this step, the endoscope and all removable components should be completely immersed in the high-level disinfectant solution. All internal channels must be fully perfused to ensure complete contact between the disinfectant and all potentially contaminated surfaces.
MEDALKAN has formulated NOSOCID PAA, high level disinfectant based on peracetic acid and hydrogen peroxide for the cold sterilisation of thermosensitive instruments and endoscopes.
NOSOCID PAA provides a full spectrum of antimicrobial activity (bactericidal, fungicidal, fully virucidal, tuberculocidal, mycobactericidal and sporicidal) in a contact time of only 5 minutes.
NOSOZYM is a highly concentrated enzymatic cleaning solution for surgical instruments and flexible endoscopes. The formulation contains a synergistic enzyme system which enzymatically degrade proteins, lipids, polysaccharides and blood residues.
NOSOZYM can be used in ultrasonic baths, automated endoscope reprocessors, washer disinfectors and immersion baths, offering flexibility across different reprocessing systems.
NOSOZYM is compatible with all major brands of endoscopes and approved by PENTAX MEDICAL®
NOSOZYM 6 PLUS is a very highly concentrated, multi- enzymatic detergent for flexible endoscopes and surgical instruments, developed to deliver superior cleaning performance against complex organic contamination.
NOSOZYM 6 PLUS can be used in ultrasonic baths, immersion baths and automatic washers, providing flexibility across different reprocessing environments.
NOSOZYM 6 PLUS is compatible with all major brands of endoscopes and approved by PENTAX MEDICAL®
NOSOCID PAA is a high level disinfectant especially formulated for the cold sterilisation of endoscopes and thermosensitive instruments. It is based on a synergy of peracetic acid and hydrogen peroxide. It combines a broad spectrum of antimicrobial activity, rapid contact times and an enhanced material compatibility.
It is recommended for the cold sterilisation of all types of endoscopes (bronchoscopes, gastroscopes, duodenoscopes, naso-laryngo-pharyngoscopes, laparoscopes, etc.), surgical instruments, anesthetic and heat-sensitive medical devices.
MEDALKAN – The Next Generation of Medical Disinfectants



