Multi enzymatic detergent for surgical instruments and endoscopes

NOSOZYM 6 PLUS is a very concentrated multienzymatic detergent specially formulated for cleaning endoscopes and surgical instruments.

Thanks to the synergy of 7 enzymes (protease, lipase, amylase, pectinase, mannanase and cellulases), it dissolves rapidly all types of organic residues such as proteins, lipids, starch, cellulose, polysaccharides and blood deposits.

It effectively removes biofilm while preserving endoscope materials.

NOSOZYM 6 PLUS is compatible with all major brands of endoscopes and approved by PENTAX MEDICAL®

NOSOZYM 6 PLUS can be used in ultrasonic baths, immersion baths or in automatic washers.


  • A synergy of highly stabilized enzymes for a powerful cleaning action
  • Removes effectively all types of organic residues
  • Dissolves the biofilm
  • Very economical
  • Does not foam
  • Prevents corrosion and instrument discoloration
  • Compatible with heat-sensitive instruments

The cleaning efficiency and biofilm reduction of NOSOZYM 6 PLUS has been tested and validated according to ISO 15883-1:2014 and ISO 15883-5:2021.


NOSOΖΥΜ 6 PLUS is compatible with most materials such as stainless steel, aluminum, glass, ceramics, hard plastics, ebonite, etc …

Ultrasonic bath

ΝΟSΟΖΥΜ 6 PLUS can be used in all common types of ultrasonic baths.

Recommended dosage: 0,5% dilution.

Endoscopes - cleaning with enzymes

NOSOZYM 6 PLUS contains a combination of multiple enzymes. The enzymes break down the soil into tiny fragments, making it water soluble and thus easier to remove by rinsing.

Use NOSOZYM 6 PLUS for endoscope cleaning:

  • by manual cleaning
  • in automated reprocessor (follow the manufacturer instructions)
NOSOZYM 6 PLUS - Multi enzymatic detergent for surgical instruments and endoscopes


  • 5 litre canister (Ref. 20033)
  • Dosing pump for 5 litre canister (Ref. 20023)

Physical properties

  • Appearance:Transparent orange solution
  • Density: 1.02 g/cm3 at 20˚C
  • pH: 7.0 – 8.0 (Neutral) at 20˚C
  • pH (0.2% – 1%): 7.0 – 8.0 (Neutral) at 20˚C
  • Odour: Mild lemon – peppermint fragrance
  • Storage: 5˚C – 35˚C
  • Stability: 3 Years
  • Biodegradability: According to OCDE 301D


Protease, lipase, amylase, pectinase, mannanase, two different cellulases, non ionic surfactants <5%, corrosion inhibitor, pH regulator, excipients.

NOSOZYM 6 PLUS is manufactured in the EU.
MEDALKAN satisfies the requirements of ISO 9001 for quality management system and the requirements of ISO 13485 for the design and manufacture of medical devices.

ISO Certification
  • CE mark according to the medical devices MDR Regulation (EU) 2017/745
  • Medical device class I