Hospitals & Clinics
Instrument Disinfection - The Challenge of Pre-disinfection
Pre-disinfection is a key early step in the instrument reprocessing workflow and plays an important role in controlling bioburden, preventing drying of organic contaminants and improving overall reprocessing effectiveness.
Immediately after use, surgical instruments are heavily contaminated with blood, proteins, lipids and other biological materials. If these soils are allowed to dry, they can become firmly fixed to instrument surfaces, making subsequent cleaning more difficult and less effective.
A pre-disinfection procedure is highly recommended for reusable and immersible medical devices prior to transport and further reprocessing.

Pre-disinfection consists of immersing soiled surgical instruments in a combined detergent and disinfectant solution such as NOSOPROTECT, before their transfer to the Central Sterile Services Department (CSSD). This step helps reduce microbial load, prevents drying of organic residues and facilitates subsequent cleaning.
If transport time is prolonged, soiled instruments should be pre-treated immediately after use and kept moist using a disinfecting spray solution such as NOSOPROTECT 100, in order to limit the risk of microbial transmission and to prevent drying of contaminants during transport.
Therefore, MEDALKAN has formulated:
- NOSOPROTECT - Highly concentrated mycobactericidal medical & surgical instrument disinfectant.
- NOSOPROTECT 100 - Foaming disinfectant spray for instrument pre-treatment.
Both NOSOPROTECT and NOSOPROTECT 100 have been developed with particular attention to material compatibility. Their formulations are designed to help protect sensitive materials and support resistance to corrosion and discoloration, thereby contributing to extended instrument lifespan and preservation of instrument performance.
NOSOPROTECT is a highly concentrated mycobactericidal instrument disinfectant combining excellent cleaning and disinfection performance in a single process.
Its advanced formulation is optimized for use on heat-sensitive materials and instrumentation, including scalpels, curettes, forceps, scissors, specula, mirrors, stethoscopes, and similar devices.
NOSOPROTECT can be used in ultrasonic and immersion baths, allowing flexible integration into reprocessing workflows.
NOSOPROTECT 100 is a disinfecting foaming spray with a high detergency efficacy for the rapid pre-disinfection of surgical instruments immediately after use.
NOSOPROTECT 100 keeps the instruments moist, protects from corrosion and avoids organic residue deposits such as blood or proteins from drying. It makes the reprocessing of instruments significantly safer and easier.
NOSOPROTECT 100 contains a complex of highly stabilized enzymes, surfactants, amines and corrosion inhibitors for an enhanced protection and cleaning action.
NOSOZYM is a highly concentrated enzymatic cleaning solution for surgical instruments and flexible endoscopes. The formulation contains a synergistic enzyme system which enzymatically degrade proteins, lipids, polysaccharides and blood residues.
NOSOZYM can be used in ultrasonic baths, automated endoscope reprocessors, washer disinfectors and immersion baths, offering flexibility across different reprocessing systems.
NOSOZYM is compatible with all major brands of endoscopes and approved by PENTAX MEDICAL®
NOSOZYM 6 PLUS is a very highly concentrated, multi- enzymatic detergent for flexible endoscopes and surgical instruments, developed to deliver superior cleaning performance against complex organic contamination.
NOSOZYM 6 PLUS can be used in ultrasonic baths, immersion baths and automatic washers, providing flexibility across different reprocessing environments.
NOSOZYM 6 PLUS is compatible with all major brands of endoscopes and approved by PENTAX MEDICAL®
NOSOCID PAA is a high level disinfectant especially formulated for the cold sterilisation of endoscopes and thermosensitive instruments. It is based on a synergy of peracetic acid and hydrogen peroxide. It combines a broad spectrum of antimicrobial activity, rapid contact times and an enhanced material compatibility.
It is recommended for the cold sterilisation of all types of endoscopes (bronchoscopes, gastroscopes, duodenoscopes, naso-laryngo-pharyngoscopes, laparoscopes, etc.), surgical instruments, anesthetic and heat-sensitive medical devices.
MEDALKAN – The Next Generation of Medical Disinfectants

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